Comparison of Parotidectomy With Observation for Treatment of Pleomorphic Adenoma in Adults.

ABSTRACT:

Importance

There is no consensus regarding optimal management of pleomorphic adenoma in adults.

Objectives

To compare parotidectomy with observation for the management of pleomorphic adenoma in patients 50 years or older by age.

Design and setting

This decision analytical model was performed from November 21, 2019, to June 15, 2020, using a Markov model. Model variables and ranges were selected based on a literature review. A 1-way sensitivity analysis was performed to evaluate the age threshold at which each algorithm, either upfront elective parotidectomy or observation, would be favored. A Monte Carlo probabilistic sensitivity analysis using variable ranges was then performed 5 times with patients in the model assigned a starting age of 50, 60, 70, 80, and 90 years

SUBMITTER: Kligerman MP 

PROVIDER: S-EPMC7516813 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature