Biomarker changes with systolic anterior motion of the mitral valve in cats with hypertrophic cardiomyopathy.

ABSTRACT:

Background

N-terminal pro B-type natriuretic peptide (NT-proBNP) and cardiac troponin-I (cTnI) are biomarkers commonly evaluated in cats with suspected heart disease. Many cats with hypertrophic cardiomyopathy (HCM) have systolic anterior motion of the mitral valve (SAM), but its influence on circulating NT-proBNP or cTnI concentrations is currently unknown.

Hypothesis/objectives

Cats with HCM and SAM (HCM^SAM+ ) have higher NT-proBNP and cTnI concentrations than do cats with HCM but without SAM (HCM^SAM- ).

Animals

One hundred forty cats with HCM: 70 with SAM and 70 without SAM.

Methods

Retrospective case-to-case study. Cats were recruited if diagnosed with HCM by echocardiography and results were available for NT-proBNP or cTnI concentrati

SUBMITTER: Seo J 

PROVIDER: S-EPMC7517492 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature