A magnetically actuated microrobot for targeted neural cell delivery and selective connection of neural networks.

ABSTRACT: There has been a great deal of interest in the development of technologies for actively manipulating neural networks in vitro, providing natural but simplified environments in a highly reproducible manner in which to study brain function and related diseases. Platforms for these in vitro neural networks require precise and selective neural connections at the target location, with minimal external influences, and measurement of neural activity to determine how neurons communicate. Here, we report a neuron-loaded microrobot for selective connection of neural networks via precise delivery to a gap between two neural clusters by an external magnetic field. In addition, the extracellular action potential was propagated from one cluster to the other through the neurons on the microrobot. The pro

SUBMITTER: Kim E 

PROVIDER: S-EPMC7518876 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature