Structural brain damage and visual disorders in children with cerebral palsy due to periventricular leukomalacia.

ABSTRACT:

Aim

To systematically explore the relationship between type and severity of brain lesion on Magnetic Resonance Imaging (MRI) and visual function in a large cohort of children with periventricular leukomalacia (PVL).

Methods

94 children with bilateral cerebral palsy (CP) and history of PVL were recruited at Stella Maris Scientific Institute in Pisa (Italy). We included data of participants (72) with at least one MRI after the age of three years and an evaluation of visual function including fixation, following, saccades, nystagmus, acuity, visual field, stereopsis and color perception. Brain lesions location and extent were assessed by a semi-quantitative MRI-scale for children with CP.

Results

Brain lesion severity strongly correlated with visual function total score

SUBMITTER: Tinelli F 

PROVIDER: S-EPMC7519396 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature