Differences in mortality in patients undergoing surgery for infective endocarditis according to age and valvular surgery.

ABSTRACT:

Background

Infective endocarditis (IE) is associated with high mortality. Surgery may improve survival and reduce complications, but the balance between benefit and harm is difficult and may be closely related to age and type of surgical intervention. We aimed to examine how age and type of left-sided surgical intervention modified mortality in patients undergoing surgery for IE.

Methods

By crosslinking nationwide Danish registries we identified patients with first-time IE undergoing surgical treatment 2000-2017. Patients were grouped by age < 60 years, 60-75 years, and ≥ 75 years. Multivariable adjusted Cox proportional hazard analysis was used to examine factors associated with 90-day mortality.

Results

We included 1767 patients with IE undergoing surgery, 735 patie

SUBMITTER: Ostergaard L 

PROVIDER: S-EPMC7519559 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature