Adult Langerhans cell histiocytosis presenting with multisystem involvement and sarcomatoid features: a case report.

ABSTRACT:

Background

Langerhans cell tumors are rare clonal disorders characterized by neoplastic proliferation of dendritic cells that can be further classified into the subtypes Langerhans cell histiocytosis and Langerhans cell sarcoma, which are rare neoplasms exhibiting aggressive features and a poor prognosis. In addition to illustrating the refractoriness and poor outcomes of multisystem Langerhans cell histiocytosis in adults, specific events in this case highlight important characteristics of disease biology that warrant detailed discussion and exposition to a wider audience.

Case presentation

We describe the case of a 42-year-old Caucasian man with Langerhans cell histiocytosis diagnosed from a lesion on the left arm that presented with constitutional symptoms, early satiety,

SUBMITTER: Aguirre LE 

PROVIDER: S-EPMC7520028 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature