Dosimetric comparison of tomotherapy and volumetric-modulated arc therapy for children with neuroblastoma.

ABSTRACT:

Importance

Irradiation treatment for pediatric patients with neuroblastoma represents a major challenge due to the pediatric dose limits for critical structures and the necessity of sufficient dose coverage of the clinical target volume for local control.

Objective

To investigate dosimetric differences between tomotherapy (TOMO) and volumetric-modulated arc therapy (VMAT) as retroperitoneal radiotherapy for children with neuroblastoma.

Methods

Eight patients who received retroperitoneal radiotherapy for neuroblastoma were selected for comparison of TOMO and VMAT treatment plans. The D_min, D_max, D_mean, D₉₅, D₂, and D₉₈ of planning target volume (PTV), conformity index (CI), heterogeneity index (HI), and

SUBMITTER: Liu X 

PROVIDER: S-EPMC7520106 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature