Levosimendan and Global Longitudinal Strain Assessment in Sepsis (GLASSES 1): a study protocol for an observational study.

ABSTRACT:

Introduction

Cardiogenic shock is a condition of low cardiac output that represents the end stage of a progressive deterioration of cardiac function. The main cause is ischaemic heart disease, but there are several non-ischaemic causes, including sepsis. The use of levosimendan in cardiogenic shock during sepsis is still under debate.

Methods

We are conducting an observational, single-centre, not-for-profit study enrolling patients aged 18-80 years old admitted to the intensive care unit with a diagnosis of septic shock. Patients will be monitored with the EV1000/VolumeView device (Edwards Lifesciences, Irvine, USA). Patients with cardiac index (CI) values <2.5 L/min/m² and/or stroke volume index (SVI) <30 mL/beat/m² are considered eligible for the stud

SUBMITTER: Cappellini I 

PROVIDER: S-EPMC7520838 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature