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Does zinc with and without iron co-supplementation have effect on motor and mental development of children? A systematic review and meta-analysis.


ABSTRACT:

Background

Effects of zinc with and without iron co-supplementation on child development are uncertain therefore the aims of this systematic review were to explore whether supplementation with zinc alone and zinc with iron in children aged 0-5 years old have beneficial or adverse effects on their mental and motor development.

Method

We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, CINAHL, Web of Science and Scopus until July 2020 and included randomized controlled trials, which assessed effects of zinc supplementation with and without iron in children less than 5 years old on mental and motor development. Data were pooled by random effects model and the Standardized Mean Differences (SMDs) with 95% confidence interval were estimated. The heterogen

SUBMITTER: Sajedi F 

PROVIDER: S-EPMC7520965 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature