Association of Low-Dose Aspirin and Survival of Women With Endometrial Cancer.

ABSTRACT:

Objective

To examine the survival outcomes in women with endometrial cancer who were taking low-dose aspirin (81-100 mg/d).

Methods

A multicenter retrospective study was conducted examining patients with stage I-IV endometrial cancer who underwent hysterectomy-based surgical staging between January 2000 and December 2013 (N=1,687). Patient demographics, medical comorbidities, medication types, tumor characteristics, and treatment patterns were correlated to survival outcomes. A Cox proportional hazard regression model was used to estimate adjusted hazard ratio for disease-free and disease-specific overall survival.

Results

One hundred fifty-eight patients (9.4%, 95% confidence interval [CI] 8.8-11.9) were taking low-dose aspirin. Median follow-up time for the study co

SUBMITTER: Matsuo K 

PROVIDER: S-EPMC7521085 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature