Novel insights into the treatment of SARS-CoV-2 infection: An overview of current clinical trials.

ABSTRACT: The emergence of the global pandemic caused by the novel SARS-CoV-2 virus has motivated scientists to find a definitive treatment or a vaccine against it in the shortest possible time. Current efforts towards this goal remain fruitless without a full understanding of the behavior of the virus and its adaptor proteins. This review provides an overview of the biological properties, functional mechanisms, and molecular components of SARS-CoV-2, along with investigational therapeutic and preventive approaches for this virus. Since the proteolytic cleavage of the S protein is critical for virus penetration into cells, a set of drugs, such as chloroquine, hydroxychloroquine, camostat mesylate have been tested in clinical trials to suppress this event. In addition to angiotensin-converting enzyme

SUBMITTER: Oroojalian F 

PROVIDER: S-EPMC7521454 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature