Erythrocyte ω-3 polyunsaturated fatty acids are inversely associated with the risk of oral cancer: a case-control study.

ABSTRACT:

Objectives

Evidence about ω-3 polyunsaturated fatty acids (ω-3 PUFAs) and oral cancer risk were limited. We aimed to evaluate the association of erythrocyte ω-3 PUFAs with the risk of oral cancer in a population from China.

Methods

Erythrocyte ω-3 PUFAs of 236 oral cancer patients and 300 controls were determined by gas chromatography. Restricted cubic spline and logistic regression were used to analyze the association between erythrocyte ω-3 PUFAs and oral cancer risk. The crude and adjusted OR with 95% CI was calculated. Stratification analysis was performed to explore the potential interaction between ω-3 PUFAs and other traditional risk factors such as smoking and drinking.

Results

Eicosapentaenoic acids (EPA), docosahexaenoic acids (DHA) and ω-3 index were negati

SUBMITTER: Chen Q 

PROVIDER: S-EPMC7522234 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature