Constructing Cu7S4@SiO2/DOX Multifunctional Nanoplatforms for Synergistic Photothermal-Chemotherapy on Melanoma Tumors.
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ABSTRACT: The integration of photothermal therapy and chemotherapy has been recognized to be an efficient strategy through the instant thermally ablation and long-term chemical inhibition, thus achieving high therapeutical effect. In the present work, we designed and prepared Cu7S4@SiO2/DOX nanocomposites and used them as efficient nanoplatforms for synergistic photothermal-chemo therapy on melanoma tumors. The Cu7S4@SiO2/DOX was constructed by firstly synthesizing Cu7S4 nanocrystals, then in situ growing SiO2 shell on the surface of Cu7S4 nanocrystals, and finally loading DOX within SiO2 shell. The Cu7S4@SiO2/DOX was composed of
SUBMITTER: Zhang L
PROVIDER: S-EPMC7522791 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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