Choroidal vascular changes in retinitis pigmentosa patients detected by optical coherence tomography angiography.

ABSTRACT:

Background

To evaluate choroidal vascular changes, including choriocapillaris (CC) and middle/large choroidal vessels, in retinitis pigmentosa (RP) patients using wide-angle optical coherence tomography angiography (OCTA) and to determine whether changes in the choroidal vascularity have a relationship with visual function and retinal structural changes.

Methods

34 patients with a confirmed diagnosis of RP and 48 controls were recruited. All patients underwent detailed ophthalmologic and imaging examinations, including two types of OCTA (Optovue, 3 × 3 mm, 6 × 6 mm; VG-200, 12 × 12 mm). CC defects were defined according to the choroidal vascular structure in five degrees. To evaluate middle and large choroidal vascular changes, the choroidal vascularity index (CVI), which wa

SUBMITTER: Shen C 

PROVIDER: S-EPMC7523071 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature