Systematic review of the impact of non-alcoholic fatty liver disease on mortality and adverse clinical outcomes for individuals with chronic kidney disease.

ABSTRACT:

Objectives

To investigate if non-alcoholic fatty liver disease (NAFLD) impacts mortality and adverse outcomes for individuals with chronic kidney disease (CKD).

Design

Systematic review.

Data sources

PubMed, EMBASE and Web of Science were searched up to 1 February 2020 with no restriction on the earliest date.

Eligibility criteria for selecting studies

Observational cohort studies that reported either the risk of all-cause mortality, incidence of non-fatal cardiovascular events (CVE) or progression of kidney disease among adults with established CKD who have NAFLD compared with those without.

Data extraction and synthesis

Two reviewers extracted data and assessed bias independently.

Results

Of 2604 records identified, 3 studies were included (UK (

SUBMITTER: Hydes T 

PROVIDER: S-EPMC7523199 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature