Bacterial diversity and prevalence of antibiotic resistance genes in the oral microbiome.

ABSTRACT:

Objectives

This study aims to describe the oral microbiome diversity and prevalence of ARGs in periodontal health and disease.

Background

The human oral cavity harbors a complex microbial community known as the oral microbiome. These organisms are regularly exposed to selective pressures, such as the usage of antibiotics, which drive evolution and acquisition of antibiotic resistance genes (ARGs). Resistance among oral bacteria jeopardizes not only antibiotic therapy for oral infections, but also extra-oral infections caused by bacterial translocation.

Methods

We carried out a cross-sectional investigation. Saliva and subgingival plaque samples were collected during a clinical exam. 16S rRNA gene sequencing was performed to assess microbial diversity. Resistance genes

SUBMITTER: Almeida VSM 

PROVIDER: S-EPMC7523989 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature