Sequence identification and expression profile of seven Dermacentor marginatus glutathione S-transferase genes.

ABSTRACT: Dermacentor marginatus is a widespread tick species and a vector of many pathogens in Eurasia. Due to the medical importance of D. marginatus, control measures are needed for this tick species. Currently tick control approaches rely mostly on acaricide application, whereas wrong and irrational acaricide use may result in drug resistance and residue problems. Vaccination as an alternative approach for tick control has been proven to be effective towards some tick species. However, immunization against D. marginatus has not yet reached satisfactory protection. The effort of in silico based analysis could predict antigenicity and identify candidates for anti-tick vaccine development. We carried out an in silico analysis of D. marginatus glutathione S-transferases (DmGSTs) in order to identify

SUBMITTER: Huercha 

PROVIDER: S-EPMC7524029 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature