Probiotic-directed modulation of gut microbiota is basal microbiome dependent.

ABSTRACT: As an effective means to improve quality of life and prevent diseases, the demand for probiotics and related products has increased in recent years. However, it is still unclear whether a particular probiotic strain will have similar beneficial effects on healthy adults from different regions. In this study, the probiotic Lactobacillus casei Zhang (LCZ) was consumed by healthy adults from six different Asian regions and the changes in gut microbiota were compared using PacBio single molecule, real-time (SMRT) sequencing technology based on samples collected before, during and after consumption of LCZ. Our results reveal that the effect of LCZ consumption on individuals was closely related to the composition of that individual's basal gut microbiota. A Gut Microbiota Variability Inde

SUBMITTER: Hou Q 

PROVIDER: S-EPMC7524168 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature