Ontology highlight
ABSTRACT:
SUBMITTER: Nagayama M
PROVIDER: S-EPMC7524366 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Nagayama Manabu M Yano Tomonori T Atarashi Koji K Tanoue Takeshi T Sekiya Mariko M Kobayashi Yasutoshi Y Sakamoto Hirotsugu H Miura Kouichi K Sunada Keijiro K Kawaguchi Takaaki T Morita Satoru S Sugita Kayoko K Narushima Seiko S Barnich Nicolas N Isayama Jun J Kiridooshi Yuko Y Shiota Atsushi A Suda Wataru W Hattori Masahira M Yamamoto Hironori H Honda Kenya K
Gut microbes 20200720 1
Dysbiotic microbiota contributes to the pathogenesis of Crohn's disease (CD) by regulating the immune system. Although pro-inflammatory microbes are probably enriched in the small intestinal (SI) mucosa, most studies have focused on fecal microbiota. This study aimed to examine jejunal and ileal mucosal specimens from patients with CD via double-balloon enteroscopy. Comparative microbiome analysis revealed that the microbiota composition of CD SI mucosa differs from that of non-CD controls, with ...[more]