Can We Improve the Preoperative Prediction of Prostate Cancer Recurrence With Multiparametric MRI?

ABSTRACT:

Introduction

The use of multiparametric magnetic resonance imaging (mpMRI) to assess prostate cancer (PCa) has increased over the past decade. We aimed to assess if preoperative mpMRI lesion score, a variable routinely available for men undergoing pre-biopsy MRI, improves the performance of commonly used preoperative predictive models for PCa recurrence.

Patients and methods

We analyzed data from 372 patients with PCa treated with radical prostatectomy in 2012 to 2017 and assessed with pre-biopsy mpMRI within 6 months prior to surgery. Suspicious areas for cancer were scored on a standardized 5-point scale. Cox regression was used to assess the association between mpMRI score and the risk of postoperative biochemical recurrence. Two different models were tested accounting fo

SUBMITTER: Capogrosso P 

PROVIDER: S-EPMC7524609 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature