Cognitive impairment and C-reactive protein in clinically stable schizophrenia outpatients: a focus on sex differences.

ABSTRACT: Although previous findings identified an association between C-reactive protein (CRP) levels, and impaired cognitive functions in patients with schizophrenia (SZ), little is currently known about the relationship between inflammation, cognition, and sex in SZ. The current study aimed to explore the association between peripheral inflammation and cognitive impairment in SZ as a function of sex. The sample included 132 clinically stable patients with SZ, of whom 82 were males (62.1%) and 50 females (37.9%). Sociodemographic data were collected, an accurate assessment was performed using the Positive and Negative Syndrome (PANSS), Clinical Assessment Interview for Negative Symptoms (CAINS), and Calgary Depression (CDS) scales, and the MATRICS Consensus Cognitive Battery (MCCB), and CRP levels

SUBMITTER: Dal Santo F 

PROVIDER: S-EPMC7524709 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature