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Sleep apnea in men is associated with altered lipid metabolism, glucose tolerance, insulin sensitivity, and body fat percentage.

ABSTRACT: PURPOSE:Obstructive sleep apnea (OSA) is associated with obesity and risk for type 2 diabetes. In this community-based study, we thoroughly investigated fatty acid metabolism, incretin response, glucose tolerance, insulin secretion and insulin sensitivity, and autonomic nerve activity in men with or without OSA. METHODS:Fifteen men without diabetes but with signs of severe OSA, defined as apnea-hypopnea index (AHI) >30, and 15 age- and BMI-matched men without OSA (AHI?

SUBMITTER: Kamble PG

PROVIDER: S-EPMC7524823 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Sleep apnea in men is associated with altered lipid metabolism, glucose tolerance, insulin sensitivity, and body fat percentage.

Kamble Prasad G PG Theorell-Haglöw Jenny J Wiklund Urban U Franklin Karl A KA Hammar Ulf U Lindberg Eva E Eriksson Jan W JW

Endocrine 20200619 1

<h4>Purpose</h4>Obstructive sleep apnea (OSA) is associated with obesity and risk for type 2 diabetes. In this community-based study, we thoroughly investigated fatty acid metabolism, incretin response, glucose tolerance, insulin secretion and insulin sensitivity, and autonomic nerve activity in men with or without OSA.<h4>Methods</h4>Fifteen men without diabetes but with signs of severe OSA, defined as apnea-hypopnea index (AHI) >30, and 15 age- and BMI-matched men without OSA (AHI < 5) were re ...[more]

PMID: 32562183

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