Use of illicit substances and violent behaviour in psychotic disorders: two nationwide case-control studies and meta-analyses.

ABSTRACT:

Background

Substance use disorder explains much of the excess risk of violent behaviour in psychotic disorders. However, it is unclear to what extent the pharmacological properties and subthreshold use of illicit substances are associated with violence.

Methods

Individuals with psychotic disorders were recruited for two nationwide projects: GROUP (N = 871) in the Netherlands and NEDEN (N = 921) in the United Kingdom. Substance use and violent behaviour were assessed with standardized instruments and multiple sources of information. First, we used logistic regression models to estimate the associations of daily and nondaily use with violence for cannabis, stimulants, depressants and hallucinogens in the GROUP and NEDEN samples separately. Adjustments were made for age, sex an

SUBMITTER: Lamsma J 

PROVIDER: S-EPMC7525769 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature