Local myocardial stiffness variations identified by high frame rate shear wave echocardiography.

ABSTRACT:

Background

Shear waves are generated by the closure of the heart valves. Significant differences in shear wave velocity have been found recently between normal myocardium and disease models of diffusely increased muscle stiffness. In this study we correlate in vivo myocardial shear wave imaging (SWI) with presence of scarred tissue, as model for local increase of stiffness. Stiffness variation is hypothesized to appear as velocity variation.

Methods

Ten healthy volunteers (group 1), 10 hypertrophic cardiomyopathy (HCM) patients without any cardiac intervention (group 2), and 10 HCM patients with prior septal reduction therapy (group 3) underwent high frame rate tissue Doppler echocardiography. The SW in the interventricular septum after aortic valve closure was mapped along

SUBMITTER: Strachinaru M 

PROVIDER: S-EPMC7525991 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature