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Significance of monocyte counts on tumor characteristics and survival outcome of women with endometrial cancer.


ABSTRACT:

Objective

Tumor-associated macrophages are known to be associated with decreased survival of patients with endometrial cancer. Given the physiological link of circulating monocytes as a progenitor of tumor-associated macrophages, monocyte counts were examined for tumor characteristics and survival in endometrial cancer.

Methods

A retrospective study was conducted to examine consecutive patients with endometrial cancer with all histologic types who underwent hysterectomy-based surgical staging between 2003 and 2013 (n=541). Preoperative monocyte counts were correlated to patient demographics, pathological findings, complete blood count results, and survival outcomes.

Results

Median monocyte counts were 0.5×10(9)/L. Monocyte counts significantly correlated with all othe

SUBMITTER: Matsuo K 

PROVIDER: S-EPMC7526038 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature