Evolving population-based statistics for rare epithelial ovarian cancers.

ABSTRACT:

Objective

To describe how population-based statistics for rare epithelial ovarian cancers are evolving.

Methods

This is a retrospective observational study examining the Surveillance, Epidemiology, and End Results Program from 1988 to 2016. Overall survival (OS) of clear cell (OCCC), mucinous (MOC), and low-grade serous (LGSOC) ovarian cancers were compared to high-grade serous ovarian cancer (HGSOC) by fitting a propensity score matching.

Results

Among 113,365 ovarian malignancies, 5780 OCCCs (5.1%), 7561 MOCs (6.7%), and 2021 LGSOCs (1.8%) were compared to 38,199 HGSOCs. OCCCs and MOCs were more likely to be diagnosed with stage I disease compared to HGSOC (57.0-59.5% versus 8.6%, P<0.001). For early-stage disease, OCCC (hazard ratio [HR] 0.91, 95% confidence interv

SUBMITTER: Matsuo K 

PROVIDER: S-EPMC7526050 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature