Fertility-sparing trachelectomy for early-stage cervical cancer: A proposal of an ideal candidate.

ABSTRACT:

Objective

To propose an ideal patient candidate with early-stage cervical cancer for undergoing fertility-sparing trachelectomy.

Methods

This nationwide, multicenter, retrospective study was conducted by the Japan Society of Obstetrics and Gynecology involving women aged <45 years with clinical stage I-II cervical cancer who had planned fertility-sparing trachelectomy and pelvic lymphadenectomy between 2009 and 2013 (n = 393). Ideal candidates were defined to have a tumor size of ≤2 cm, no lymph node metastasis, no deep stromal invasion, and no high-risk histology (n = 284, 69.6%). Less-ideal candidates were defined to have any one of these four characteristics (n = 109, 30.4%). Propensity score inverse probability of treatment weighting was used to assess survival outcomes.

SUBMITTER: Machida H 

PROVIDER: S-EPMC7526083 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature