Sperm impairing microbial factor: potential candidate for male contraception.

ABSTRACT:

Background

Despite significant advances in contraceptive options for women, vasectomy and condoms are the only options available for male contraception. Due to this limitation, the burden of contraception resides on the shoulders of females only. Therefore, there is an urgent need to develop a safe, effective and reversible method of contraception for men. Amongst the alternative approaches, microbial derived products are gaining attention of the scientific world to combat unintended pregnancies. Earlier in our laboratory, sperm impairing microbial factor (Sperm immobilization factor) isolated from Staphylococcus aureus has shown excellent contraceptive efficacy in female mice. Keeping this in mind, the present study was carried out to exploit the sperm immobilization factor (SIF)

SUBMITTER: Chauhan A 

PROVIDER: S-EPMC7526221 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature