Infection deteriorating hepatitis B virus related acute-on-chronic liver failure: a retrospective cohort study.

ABSTRACT:

Background

Infection is common in acute-on-chronic liver failure (ACLF), which may worsen the clinical condition and prognosis. However, the characteristics of infection and its influence on prognosis in hepatitis B virus related ACLF (HBV-ACLF) as defined by the European Association for the Study of the Liver (EASL) have not been clarified. We aimed to investigate the characteristics of infection and its influence on mortality in patients with HBV-ACLF defined by EASL in China.

Methods

We performed a retrospective cohort study in patients with HBV-ACLF defined by EASL in a single center from January 2015 to December 2017. These patients were divided into two groups with and without infection. The incidence, sites of infection, isolated strains, and risk factors associated w

SUBMITTER: Zhai XR 

PROVIDER: S-EPMC7526233 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature