External validation of three atherosclerotic cardiovascular disease risk equations in rural areas of Xinjiang, China.

ABSTRACT:

Background

To externally validate the Prediction for ASCVD Risk in China (PAR) risk equation for predicting the 5-year atherosclerotic cardiovascular disease (ASCVD) risk in the Uyghur and Kazakh populations from rural areas in northwestern China and compare its performance with those of the pooled cohort equations (PCE) and Framingham risk score (FRS).

Methods

The final analysis included 3347 subjects aged 40-74 years without CVD at baseline. The 5-year ASCVD risk was calculated using the PAR, PCE, and FRS. Discrimination, calibration, and clinical usefulness of the three equations in predicting the 5-year ASCVD risk were assessed before and after recalibration.

Results

Of 3347 included subjects, 1839 were female. We observed 286 ASCVD events in within 5-year follow-

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC7526265 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature