Long-term tracking of fasting blood glucose variability and peripheral artery disease in people without diabetes.

ABSTRACT:

Introduction

Long-term changes of fasting blood glucose (FBG) in relation to lower-extremity peripheral artery disease (lower-extremity PAD) in people without diabetes has barely been reported. Our study aimed to investigate the association between FBG variability and the incidence of lower-extremity PAD in people without diabetes.

Research design and methods

We included 7699 participants without prior lower-extremity PAD and diabetes from the Atherosclerosis Risk in Communities study in the final analysis. At least two measurements of FBG were required during follow-up. Variability of FBG was identified using SD, coefficient of variation (CV), variability independent of the mean (VIM) and average real variability. Lower-extremity PAD was defined as an ankle brachial index <

SUBMITTER: Sun XT 

PROVIDER: S-EPMC7526273 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature