Alpha coma EEG pattern in patients with severe COVID-19 related encephalopathy.

ABSTRACT:

Objective

Encephalopathy is a major neurological complication of severe Coronavirus Disease 2019 (COVID-19), but has not been fully defined yet. Further, it remains unclear whether neurological manifestations are primarily due to neurotropism of the virus, or indirect effects, like cerebral hypoxia.

Methods

We analysed the electroencephalograms (EEGs) of 19 consecutive patients with laboratory-confirmed COVID-19, performed at peak disease severity as part of their clinical management. Disease severity, respiratory failure, immune and metabolic dysfunction, sedation status, and neurological examination on the day of the EEG were noted.

Results

Severe encephalopathy was confirmed in 13 patients, all with severe COVID-19; 10 remained comatose off sedation, and five of th

SUBMITTER: Koutroumanidis M 

PROVIDER: S-EPMC7527310 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature