Management of Children With Fever at Risk for Pediatric Sepsis: A Prospective Study in Pediatric Emergency Care.

ABSTRACT: Objective: To study warning signs of serious infections in febrile children presenting to PED, ascertain their risk of having sepsis, and evaluate their management. Design: Prospective observational study. Setting: A single pediatric emergency department (PED). Participants: Febrile children, aged 1 month-16 years, with >= 1 warning signs of sepsis. Interventions and Main outcome measures: Clinical characteristics, including different thresholds for tachycardia and tachypnoea, and their association with (1) delivery of pediatric sepsis 6 (PS6) interventions, (2) final diagnosis of invasive bacterial infection (IBI), (3) the risk for pediatric intensive care unit (PICU) admission, and (4) death. Results: Forty-one percent of 5,156 febrile children h

SUBMITTER: Nijman RG 

PROVIDER: S-EPMC7527403 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature