Functional connectivity of the irritative zone identified by electrical source imaging, and EEG-correlated fMRI analyses.

ABSTRACT:

Objective

The irritative zone - the area generating epileptic spikes - can be studied non-invasively during the interictal period using Electrical Source Imaging (ESI) and simultaneous electroencephalography-functional magnetic resonance imaging (EEG-fMRI). Although the techniques yield results which may overlap spatially, differences in spatial localization of the irritative zone within the same patient are consistently observed. To investigate this discrepancy, we used Blood Oxygenation Level Dependent (BOLD) functional connectivity measures to examine the underlying relationship between ESI and EEG-fMRI findings.

Methods

Fifteen patients (age 20-54), who underwent presurgical epilepsy investigation, were scanned using a single-session resting-state EEG-fMRI protocol. Stru

SUBMITTER: Urriola J 

PROVIDER: S-EPMC7527619 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature