Identification of Signatures of Selection by Whole-Genome Resequencing of a Chinese Native Pig.

ABSTRACT: Identification of genomic signatures of selection that help reveal genetic mechanisms underlying traits in domesticated pigs is of importance. Anqing six-end-white pig (ASP), a representative of the native breeds in China, has many distinguishing phenotypic characteristics. To identify the genomic signatures of selection of the ASP, whole-genome sequencing of 20 ASPs produced 469.01 Gb of sequence data and more than 26 million single-nucleotide polymorphisms. Combining these data with the available whole genomes of 13 Chinese wild boars, 157 selected regions harboring 48 protein-coding genes were identified by applying the polymorphism levels (θπ) and genetic differentiation (F _ST ) based cross approaches. The genes found to be positively selected in ASP are involv

SUBMITTER: Zhang W 

PROVIDER: S-EPMC7527633 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature