Prognostic Value of Prerevascularization Fractional Flow Reserve Mediated by the Postrevascularization Level.

ABSTRACT:

Importance

The prognostic value of pre-percutaneous coronary intervention (PCI) fractional flow reserve (FFR) may be associated with the post-PCI FFR and their interaction. To correctly interpret the prognostic value of pre-PCI FFR, it is essential to understand to what extent the association of pre-PCI FFR with clinical outcomes is explained by post-PCI FFR.

Objective

To investigate the extent to which post-PCI FFR mediates the association of pre-PCI FFR with vessel-related outcomes using an international, multicenter collaboration registry.

Design, setting, and participants

This cohort study used pooled patient data from 4 international FFR registries. A total of 1488 patients with pre-PCI FFR of 0.80 or less who underwent elective PCI were included. Data collection

SUBMITTER: Hamaya R 

PROVIDER: S-EPMC7527875 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature