Five-Year Health Status After Self-expanding Transcatheter or Surgical Aortic Valve Replacement in High-risk Patients With Severe Aortic Stenosis.

ABSTRACT:

Importance

In the CoreValve High-Risk Trial, patients with severe symptomatic aortic stenosis had similar clinical outcomes with transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR) over 5 years of follow-up, with mortality rates of more than 50% in both groups.

Objective

To describe the long-term health status of surviving patients randomized to self-expanding TAVR vs SAVR.

Design, setting, and participants

This randomized clinical trial included patients at high surgical risk with severe aortic stenosis who completed a baseline Kansas City Cardiomyopathy Questionnaire (KCCQ) and were randomized to either self-expanding TAVR or SAVR from 45 US clinical sites. Patients were enrolled from February 2011 to September 2012. Analysis be

SUBMITTER: Arnold SV 

PROVIDER: S-EPMC7527937 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature