Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak.

ABSTRACT:

Background

Long non-coding RNA (lncRNA) as an important regulator has been demonstrated playing an indispensable role in the biological process of hair follicles (HFs) growth. However, their function and expression profile in the HFs cycle of yak are yet unknown. Only a few functional lncRNAs have been identified, partly due to the low sequence conservation and lack of identified conserved properties in lncRNAs. Here, lncRNA-seq was employed to detect the expression profile of lncRNAs during the HFs cycle of yak, and the sequence conservation of two datasets between yak and cashmere goat during the HFs cycle was analyzed.

Results

A total of 2884 lncRNAs were identified in 5 phases (Jan., Mar., Jun., Aug., and Oct.) during the HFs cycle of yak. Then, differential expression a

SUBMITTER: Zhang X 

PROVIDER: S-EPMC7528256 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature