Nature of adverse events with opioids in hospitalised patients: a post-hoc analysis of three patient record review studies.

ABSTRACT:

Objective

Opioids are increasingly prescribed and frequently involved in adverse drug events (ADEs). The underlying nature of opioid-related ADEs (ORADEs) is however understudied. This hampers our understanding of risks related to opioid use during hospitalisation and when designing interventions. Therefore, we provided a description of the nature of ORADEs.

Design

A post-hoc analysis of data collected during three retrospective patient record review studies (in 2008, 2011/2012 and 2015/2016).

Setting

The three record review studies were conducted in 32 Dutch hospitals.

Participants

A total of 10 917 patient records were assessed by trained nurses and physicians.

Outcome measures

Per identified ORADE, we described preventability, type of medication error

SUBMITTER: Schutijser BCFM 

PROVIDER: S-EPMC7528356 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature