Dietary nicotine intake and risk of Parkinson disease: a prospective study.

ABSTRACT:

Background

Tobacco use was observed to be associated with a lower risk of Parkinson disease (PD) in previous epidemiologic studies, with nicotine as a potential candidate. The association between dietary nicotine and PD risk has, however, not been examined in prospective studies yet.

Objectives

We aimed to examine prospectively the association between dietary nicotine intake and subsequent PD risk among never-smokers.

Methods

The current study was based on never-smoker participants from 2 large prospective cohorts: the Nurses' Health Study (n = 31,615) and the Health Professionals Follow-up Study (n = 19,523). The studies contained information on dietary nicotine intake from 1986 from validated FFQs. Dietary nicotine intake was calculated based on consumption of peppe

SUBMITTER: Ma C 

PROVIDER: S-EPMC7528555 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature