Predictors of CNS-Active Medication Use and Polypharmacy Among Homebound Older Adults With Depression.

ABSTRACT:

Objective

The authors assessed central nervous system (CNS) polypharmacy among low-income, racially diverse homebound older adults with depression (N=277) and its associations with the participants' ratings of depressive symptoms and pain.

Methods

CNS-active and other psychotropic and analgesic medications intake was collected from patients' medication containers. Depressive symptoms were assessed with the 24-item Hamilton Depression Rating Scale, and pain intensity was measured on an 11-point numerical rating scale. Covariates were disability (World Health Organization Disability Assessment Schedule 2.0) and perceived social support (Multidimensional Scale of Perceived Social Support).

Results

Of the patients, 16% engaged in CNS polypharmacy, taking three or more CNS

SUBMITTER: Choi NG 

PROVIDER: S-EPMC7528951 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature