Prediction of true Helicobacter pylori-uninfected status using a combination of age, serum antibody and pepsinogen: Logistic regression analysis.

ABSTRACT:

Introduction

To prevent gastric cancer, it is important to accurately determine the presence of Helicobacter pylori (HP) infection. However, correctly identifying HP-uninfected individuals is difficult when using the combination of HP antibody and pepsinogen (PG).

Objective

The aim of this study was to discriminate true HP-uninfected individuals from others without the need for endoscopic examination.

Methods

A total of 684 subjects with no history of HP eradication who underwent a medical checkup at our hospital were enrolled. The "true uninfected individuals" were determined by a negative stool antigen test and no endoscopic findings of HP-associated gastritis. HP antibody was measured by the latex immunoassay method. Logistic regression analysis using a combination

SUBMITTER: Takayama T 

PROVIDER: S-EPMC7529238 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature