Role of radiation therapy in node-negative esophageal cancer: A propensity-matched analysis.

ABSTRACT:

Background

This study investigated the prognostic impact of (neo-)adjuvant radiation therapies in early stage esophageal cancer.

Methods

A retrospective analysis using the Surveillance, Epidemiology, and End Results (SEER) database was conducted from 2004 to 2016. Patients with pathologically staged T1-4N0M0 esophageal cancer were divided into two treatment groups: (i) neoadjuvant radiotherapy followed by surgery; and (ii) upfront esophagectomy followed by adjuvant radiotherapy. Propensity scored match and Cox proportional hazards model were used to identify covariates associated with overall survival and cancer-specific survival.

Results

There were 821 patients selected, of whom 588 (71.6%) received neoadjuvant radiotherapy and 233 (28.4%) received adjuvant radiother

SUBMITTER: Gao HJ 

PROVIDER: S-EPMC7529582 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature