Markers of cognitive reserve and dementia incidence in the English Longitudinal Study of Ageing.

ABSTRACT:

Background

In the current climate of an ageing population, it is imperative to identify preventive measures for dementia.

Aims

We implemented a multifaceted index of cognitive reserve markers and investigated dementia incidence over 15 years of follow-up in a representative sample of the English population.

Method

Data were 12 280 participants aged ≥50 years from the English Longitudinal Study of Ageing, free from dementia at their baseline assessments during wave 1 (2002-2003), 3 (2006-2007) or 4 (2008-2009), and followed up until wave 8 (2016-2017). The Cognitive Reserve Index was constructed as a composite measure of education, occupation and leisure activities, using a standardised questionnaire. Cox proportional hazards regression models were used to estimate the

SUBMITTER: Almeida-Meza P 

PROVIDER: S-EPMC7529639 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature