Higher dose weekly fluoxetine in hemodialysis patients: A case series report.

ABSTRACT:

Objective

The antidepressant medication fluoxetine at 90 mg dosed weekly is as effective and safe as standard formulation fluoxetine 20 mg dosed daily in patients with major depressive disorder. Weekly fluoxetine has not been well studied in hemodialysis patients, and doses beyond 90 mg/week have not been described in this population. This case series, derived from a larger study on depression in hemodialysis patients, describes the use of weekly fluoxetine at dosages beyond 90 mg/week.

Method

Hemodialysis patients with depressive symptom severity scored ≥10 on the 9-item Patient Health Questionnaire and major depressive disorder confirmed with Mini International Neuropsychiatric Interview were initially prescribed daily fluoxetine for two weeks and then transitioned to week

SUBMITTER: Kauffman KM 

PROVIDER: S-EPMC7529646 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature