Association of sleep quality with telomere length, a marker of cellular aging: A retrospective cohort study of older adults in the United States.

ABSTRACT:

Background

Sleep quality is a risk factor for age-related diseases, and although the underlying mechanisms remain unclear, the effects of poor sleep quality on telomere length (TL) may play a role.

Objective

The objective of the study was to evaluate the independent association between sleep quality and salivary TL in a large sample of older adults.

Design

We adopted a retrospective cohort design, and participants comprised 5,268 adults drawn from the Health and Retirement Study. We used the 2006 (baseline) and 2008 (follow-up) waves. Baseline sleep quality was assessed using 4 Likert scale questions (trouble falling asleep, waking up during the night, waking up too early and not being able to fall sleep again, and feeling well rested in the morning). The TL was asses

SUBMITTER: Iloabuchi C 

PROVIDER: S-EPMC7529649 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature