Association between family history of suicide attempt and neurocognitive functioning in community youth.

ABSTRACT:

Background

Suicidal behavior is highly familial. Neurocognitive deficits have been proposed as an endophenotype for suicide risk that may contribute to the familial transmission of suicide. Yet, there is a lack of research on the neurocognitive functioning of first-degree biological relatives of suicide attempters. The aim of the present study is to conduct the largest investigation to date of neurocognitive functioning in community youth with a family history of a fatal or nonfatal suicide attempt (FH).

Methods

Participants aged 8-21 years from the Philadelphia Neurodevelopmental Cohort completed detailed clinical and neurocognitive evaluations. A subsample of 501 participants with a FH was matched to a comparison group of 3,006 participants without a family history of suic

SUBMITTER: Jones JD 

PROVIDER: S-EPMC7529718 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature