Ontology highlight
ABSTRACT:
SUBMITTER: Kim S
PROVIDER: S-EPMC7530005 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Kim Seungil S Ye Sang-Ho SH Adamo Arianna A Orizondo Ryan A RA Jo Jaehyuk J Cho Sung Kwon SK Wagner William R WR
Journal of materials chemistry. B 20200901 36
Polydimethylsiloxane (PDMS) is commonly used in medical devices because it is non-toxic and stable against oxidative stress. Relatively high blood platelet adhesion and the need for chemical crosslinking through curing, however, limit its utility. In this research, a biostable PDMS-based polyurethane-urea bearing zwitterion sulfobetaine (PDMS-SB-UU) was synthesized for potential use in the fabrication or coating of blood-contacting devices, such as a conduits, artificial lungs, and microfluidic ...[more]