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Transcriptional modulation of AREB-1 by CRISPRa improves plant physiological performance under severe water deficit.


ABSTRACT: Plants are sessile organisms, which are vulnerable to environmental stresses. As such, plants have developed multiple molecular, physiological, and cellular mechanisms to cope with natural stressors. However, these environmental adversities, including drought, are sources of the main agribusiness problems since they interfere with plant growth and productivity. Particularly under water deprivation conditions, the abscisic acid-responsive element-binding protein AREB1/ABF2 plays an important role in drought stress response and physiological adaptation. In this investigation, we provide substantial confirmation for the role of AREB1/ABF2 in plant survival under severe water deficit using the CRISPR activation (CRISPRa) technique to enhance the AREB1 gene expression. In our strategy, the inac

SUBMITTER: de Melo BP 

PROVIDER: S-EPMC7530729 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature