Ontology highlight
ABSTRACT:
SUBMITTER: Stella A
PROVIDER: S-EPMC7530822 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Stella Alessandro A Lamkanfi Mohamed M Portincasa Piero P
Frontiers in immunology 20200918
Familial Mediterranean Fever (FMF) and COVID-19 show a remarkable overlap of clinical symptoms and similar laboratory findings. Both are characterized by fever, abdominal/chest pain, elevation of C-reactive protein, and leukocytosis. In addition, colchicine and IL-1 inhibitors treatments that are effective in controlling inflammation in FMF patients have recently been proposed for off-label use in COVID-19 patients. Thus, FMF may resemble a milder recapitulation of the cytokine storm that is a h ...[more]